That is while assumptions on the future of Tehran-Washington relations during Biden’s tenure and achieving a broader agreement is a very tough task, keeping in mind the age-long distrust between the two countries, of which the enemies of Iran are well aware, and yet they are not willing for least tension level decrease in the region; therefore, predicting tense security conditions during the next four years in the region, in which the terrorist groups, especially ISIS will play major roles, is quite predictable.