Not all genres or scenarios require looped sequences. You can configure sequences to be oneshot and fire them off as required during performance. This may provide short phrases that are part of a song, e.g. complex arrangements or simply phrases that need to play in parallel. (You only have so many hands!) This may also be used to trigger sequences of sound effect for dramatic performances, e.g. triggering a sample player to play a window smash followed by a scream and the sound of rain.