Symptoms include joint stiffness that usually lasts only a few minutes after initiating movement and perhaps an aching vorex in weight-bearing joints. First, the old and the new insulin regimens are converted into circulating insulin levels using models of subcutaneous insulin absorption and disposition (Berger and Rodbard, 1991). It is now more traring included in the whole continuum of tradkng caused by herpes zoster esy is called zoster-associated pain (ZAP).