The musk deer in Asia differ genetically at the karzotype level, with chromosome number ranging from 8 to 48. The 3D orientation of the genome in the nucleus is the 3D construction plan of the organism through position and spatial effects of gene control. TEs link the bauplan together via Hoogsteen basepairing with lncRNAs. The genome is simply reshuffled and this determines how the bauplan is executed. No new genes required and this type of evoltion is instant, one-few generation(s). This is the new standard to understand biological changes. It suits both OEC and YEC.