Second, the order of the subtraction in the difference doesn’t matter so long as you are consistent and tailor your interpretations accordingly. In other words, using a point estimate of \(\widehat{p}_{seed} - \widehat{p}_{control}\) or \(\widehat{p}_{control} - \widehat{p}_{seed}\) does not make a material difference, you just need to stay consistent and interpret your results accordingly.