Btw illsince1977, if you look at the Renew life formula and you will notice that the proportion of B. strains in that formula is very very high. Similiarly if you took the B. strain high formulas from customprobiotics, they will work. I am surprised Culturelle did not work for you though, becos of all the L. strains that is one of the best. There might be a detox process involved with that in you.