Values were expressed as means ± SD. The frequency distribution of haplotypes and the association of genotypes with hypertension were analyzed using a chi-squared test. Comparisons of some indexes between the EH and NT groups, including SBP, DBP and BMI, were made using Students' t-test. To test for an association between each SNP and hypertension, we computed the overall genotypic test of association and the three genetic models (dominant, additive, and recessive). A multinomial logistic regression was used to study the effect of E-selectin T1880C, C602A and T1559C variants on hypertension status to allow incorporation of other variables into the model. All tests of association were adjusted for age and gender. Analyses of case-control-biased haplotype, linkage disequilibrium, and Hardy-Weinberg equilibrium were performed using SNPAlyze, version 7.0 Pro (Dynacom Co., Ltd, Mobara, Japan). All analyses were performed using SPSS v.11.5 (SPSS Inc., Chicago, USA) statistical analysis software. A two-tailed P-value < 0.05 was considered to be statistically significant [12].