Today people are predisposed to various diseases based on their way of living and occupational habits which called as life style diseases. In developing countries, people running behind the money with neglecting health status caused by sedentary life style, erect posture, lack of exercise results in various spinal problems which ultimately turns into one of the non- communicable diseases like Gridhrasi. According to modern Gridhrasi can be correlate with Sciatica. The prevalence of Sciatica ranges from 13% to 40%. Grudhrasi word itself defines the disease i.e. “Gridhra” like walking. Gridhrasi is the most common Vata-Vyadhi explained under the heading of Nanatmaja Vata-Vyadhi. Gridhrasi shows lakshanas like Shula, Toda, Stambha, Gaurava, Padasupatata. It is most common during 40s & 50s age group. Present paper aimed to highlight the detail review about Gridhrasi, impact of Sedentary lifestyle on Gridhrasi and its management mentioned in various classical texts.