Low vision therapies Despite the success of intravitreal anti-VEGF pharmacotherapy, a significant number of patients with AMD will ultimately progress to bilateral central blindness, for which few therapeutic options exist. The implantable miniature telescope can provide magnification up to factor of 2.7; its use improved visual acuity by 2 lines in the pivotal FDA trials. However, corneal decompensation due to endothelial cell loss is projected to bring the corneal transplant rate to 5% at 5 years after the implantation surgery.