Defy aging with DefenAge. Clinically proven to reduce the signs of aging, DefenAge is the first and only product in the market today to use 4th generation stem cell technology. This revolutionary skincare product has been found to brighten age spots, minimize pores, even out skin tone, smooth fine lines and wrinkles, and revive moisture in the skin. DefenAge products available at Renew MD include the 24/7 Barrier Repair Cream, 8-in-1 BioSerum, and 2-Minute Reveal Masque.