-- Database schema
| Classification : GeneID [ TEXT ] primary_key , Localization [ TEXT ] | Genes : GeneID [ TEXT ] Genes.GeneID = Classification.GeneID , Essential [ TEXT ] , Class [ TEXT ] , Complex [ TEXT ] , Phenotype [ TEXT ] , Motif [ TEXT ] , Chromosome [ INTEGER ] , Function [ TEXT ] , Localization [ TEXT ] | Interactions : GeneID1 [ TEXT ] Interactions.GeneID1 = Classification.GeneID , GeneID2 [ TEXT ] Interactions.GeneID2 = Classification.GeneID , Type [ TEXT ] , Expression_Corr [ REAL ] |
-- -- Which negatively correlated, genetically interacting genes are non-essential? What percentage do they represent with respect to those that are essential?

SELECT CAST(COUNT(T1.GeneID) AS REAL) * 100 / ( SELECT COUNT(T1.GeneID) FROM Genes AS T1 INNER JOIN Interactions AS T2 ON T1.GeneID = T2.GeneID1 WHERE T2.Expression_Corr < 0 ) FROM Genes AS T1 INNER JOIN Interactions AS T2 ON T1.GeneID = T2.GeneID1 WHERE T2.Expression_Corr < 0 AND T1.Essential = 'Non-Essential';