Data mining in situ gene expression patterns at cellular resolution
In the post-genomic era, large-scale efforts have begun to characterize the role of gene products. Several of these efforts aim to systematically discover the activity of all /spl sim/20,000 genes throughout functionally complex tissue specimens such as embryo and the mature brain. By applying a subdivision-based deformable model of the brain, we rapidly organize spatial gene expression data into a common coordinate system. Doing this enables powerful queries, comparisons, and associations of the data.