State-space analysis of ventricular/vascular coupling
The state-space analysis technique is applied to characterizing the time-varying interaction between the left ventricle and systematic vascular bed. An analog model of the circulatory system is developed. Pressure and flow waveforms in the system are computed by numerically integrating the five simultaneous state equations that represent the system dynamics. The model-predicted waveforms agree well with the psychological responses regarding the changes in peripheral resistance, vascular capacitance, viscoelastic loss, aortic valve stenosis, and intraaortic balloon pumping.<<ETX>>