Automatic identification of lung abnormalities in chest spiral CT scans
Our aim is to develop a fully automatic computer-assisted diagnosis (CAD) system for lung cancer screening using chest spiral CT scans. A screening program on 1000 subjects aims at quantification of the effectiveness of low dose spiral CT scans for early diagnosis of lung cancer, and evaluation of its possible impact on improving the mortality rate of cancer patients. The paper presents an image analysis system for 3D reconstruction of the lungs and trachea, detection of lung abnormalities, identification/classification of these abnormalities with respect to specific diagnosis, and distributed visualization of the results over computer networks. We present two novel approaches for segmentation of the lung tissues from the surrounding structures in the chest cavity, and detection of abnormalities in the lungs. The segmentation algorithm is hierarchical, first isolating the background from the chest cavity, then isolating the lungs from surrounding structures (e.g., ribs, liver, and other organs). Abnormalities in the lungs are detected by analyzing the segmented lung tissues and extracting the isolated lumps that appear in various connected regions. 3D reconstructions are also generated for these abnormalities, to be used for subsequent identification/classification steps. Results on 50 subjects are shown, and have been evaluated against radiologists. Our image analysis approach has provided comparable results with respect to the experts. The approach is quite fast, and lends itself to distributed visualization over computer networks.