A Methodology for Non-Invasive 3-D Surveillance of Arteriovenous Fistulae Using Freehand Ultrasound
Objective: Surveillance techniques for arteriovenous fistulae are required to maintain functional vascular access, with two-dimensional duplex ultrasound the most widely used imaging modality. This paper presents a surveillance method for an arteriovenous fistula using a freehand three-dimensional (3-D) ultrasound system. A patient-case study highlights the applicability in a clinical environment. Methods: The freehand ultrasound system uses optical tracking to determine the vascular probe location, and as the probe is swept down a patient's arm, each B-mode slice is spatially arranged to be post-processed as a volume. The volume is segmented to obtain the 3-D vasculature for high detail analysis. Results: The results follow a patient with stenosis, undergoing surgery to have a stent placement. A surveillance scan was taken pre-surgery, postsurgery, and at a two-month follow-up. Vasculature changes are quantified using detailed analysis, and the benefits of using 3-D imaging are shown through 3-D printing and visualization. Conclusion and significance:  Non-invasive 3-D surveillance of arteriovenous fistulae is possible, and a patient-specific geometry was created using ultrasound and optical tracking. Access to this non-invasive 3-D surveillance technique will enable future studies to determine patient-specific remodeling behavior, in terms of geometry and hemodynamics over time.