Extracellular recording from multiple neighboring cells: a maximum-likelihood solution to the spike-separation problem
In recent years considerable attention among extracellular electrophysiologists has focused on the problem of simultaneously recording the activity of multiple neurons in behaving animals. Such recordings, it is hoped, will provide much-needed insight into the dynamics of neural ensemble computation and coding. Of particular interest are recordings from neighboring neurons, for example cells that lie within a single column of neocortex Such cells are likely to share functional roles and to possess the anatomical interConnectivity needed for ensemble coding, making them plausible participants in local computational and signaling circuits.