MODULATION OF THE FREQUENCY PREFERENCE AND ATTRACTOR STRUCTURE OF PREFRONTAL CORTICAL NEURONS
Neurons in vitro respond to repetitive injection of the same fluctuating input current with reproducible patterns of precisely timed action potentials. These spike patterns, called attractors, are robust against slow drifts in neuronal response properties that occur during experiments, the effects of intrinsic membrane noise, and small changes in the input. Larger variations in the input lead to new spike patterns that may have different number of spikes (spike insertions or deletions) and different spike times.