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  # **ZymCTRL**
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- ZymCTRL (Enzyme Control) ([Paper presented @ NeurIPS Machine Learning for Structural Biology workshop - December 2022](https://www.mlsb.io/papers_2022/ZymCTRL_a_conditional_language_model_for_the_controllable_generation_of_artificial_enzymes.pdf))
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  is a conditional language model for the generation of artificial functional enzymes. It was trained on the entire BRENDA database of enzymes, comprising over 37 M sequences.
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  Given a user-defined Enzymatic Commission (EC) number, the model generates protein sequences that fulfill that catalytic reaction.
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  The generated sequences are ordered, globular, and distant to natural ones, while their intended catalytic properties match those defined by users.
 
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  # **ZymCTRL**
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+ ZymCTRL (Enzyme Control) ([ see preprint ](https://www.biorxiv.org/content/10.1101/2024.05.03.592223v1))
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  is a conditional language model for the generation of artificial functional enzymes. It was trained on the entire BRENDA database of enzymes, comprising over 37 M sequences.
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  Given a user-defined Enzymatic Commission (EC) number, the model generates protein sequences that fulfill that catalytic reaction.
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  The generated sequences are ordered, globular, and distant to natural ones, while their intended catalytic properties match those defined by users.